Microscopic Anatomy of Skeletal Muscle

Microscopic Anatomy of Skeletal Muscle - Microscopic...

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Microscopic Anatomy of Skeletal Muscle: - skeletal muscle cells long (hundreds of cm) & wide; multinucleate - sarcolemma: plasma membrane of muscle - sarcoplasm: like cytoplasm of normal cell; contains many glycosomes (store glycogen) & myoglobin (carries & stores oxygen) - myofibrils: contractile elements of skeletal muscle o composed of thin filaments ( ) & thick filaments ( myosin ) o myosin that bind actin o tropomyosin covers myosin binding sites on actin molecules in resting muscle o troponin complex o striations result from alternating dark A bands (thick filaments with overlapping thin filaments) & I bands (thin filaments) o A bands have lighter central H zone (no thin filaments) with central darker M line (desmin protein) o I bands have darker central
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Microscopic Anatomy of Skeletal Muscle - Microscopic...

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