Microscopic anatomy of stomach

Microscopic anatomy of stomach - Microscopic anatomy of...

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Microscopic anatomy of stomach o 3 layers of smooth muscle in muscularis externa (has innermost oblique layer) o mucosa: simple columnar epithelium with goblet cells that secrete a protective alkaline mucus o mucosa folds inward to form gastric pits & deeper gastric glands that secrete gastric juice secretory cells of gastric glands : mucous neck cells : in upper “neck” region; secrete acidic mucus parietal cells : in middle region; secrete hydrochloric acid (HCl) and intrinsic factor (necessary for vitamin B 12 absorption in small intestine) chief cells : in basal region; produce pepsinogen (precursor of enzyme pepsin, a protease) enteroendocrine cells somatostatin) o G cells : secrete gastrin - mucosal barrier : protects stomach mucosa from acidic conditions inside stomach o thick alkaline mucus o epithelial cells of mucosa joined by tight junctions o in deep regions of gastric glands, plasma membrane is impermeable to HCl
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Microscopic anatomy of stomach - Microscopic anatomy of...

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