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Unformatted text preview: Weekly and monthly preparations are also available which help reduce medication side effects and the number of tablets taken on a daily basis. Surgery is still sometimes needed to replace joints or remove resistant and painful areas of bone. Intra-articular injections can be useful to differentiate between bone and joint disease. In cases of osteosarcoma amputation is typically required to prevent spread. Prognosis If diagnosed early and the appropriate treatment steps are put in place many patients enjoy a symptomless normal adult life. The most serious complication is the development osteosarcoma (less that 1% of cases) which typically has a poor prognosis in regards to bone salvation, many patients with osteosarcoma die within 12 months of diagnosis. Prevention There is no means of preventing the onset of Pagets disease; however the symptoms can be controlled with good medication compliance....
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- Fall '10