Pernicious anaemia Epidemiology

Pernicious anaemia Epidemiology - Pernicious anaemia...

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Pernicious anaemia Epidemiology Pernicious anaemia is most common in Northern Europe but it does occur worldwide. There are an estimated 6,000 cases each year in the UK. Typically women are more affected than men and the peak age of incidence is around the age of 60. It is more common in those with blue eyes, early greying hair and the blood group A. There is a family history in 1/3 rd of cases. Diagnosis If anaemia is suspected a blood sample can be taken and sent for analysis in a laboratory. The blood of a patient with Pernicious Anaemia has the following characteristics:- Low haemoglobin levels Abnormally large, fragile red blood cells Immature forms of red blood cells present in the blood Diagnosis can be confirmed by assaying serum B12 levels and looking for antibodies directed at Parietal cells and IF. In cases where antibodies are not found further investigations may be needed to elicit the cause. Treatment
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Pernicious anaemia Epidemiology - Pernicious anaemia...

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