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Prostate cance1 - which around 10,000 die of it Many...

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Prostate cancer Causes The most important risk factors are: Increased testosterone Increased age Positive family history However, it has been said that if a man lives long enough he will end up with prostate cancer at some point. Most adenocarcinomas arise from peripheral zone of prostate. The spread can be local (seminal vesicles, bladder, rectum), lymphatic or haematogenously (sclerotic bony lesions). (2° to bone = breast, lung, thyroid, prostate and renal. All osteolytic except prostate which is sclerotic) Epidemiology Prostate cancer develops primarily in men over fifty. It is the most common type of cancer in men in the United States, with 186,000 new cases in 2008 and 28,600 deaths. It is the second leading cause of cancer death in U.S. men after lung cancer. In the United Kingdom it is also the second most common cause of cancer death after lung cancer, where around 35,000 cases are diagnosed every year and of
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Unformatted text preview: which around 10,000 die of it. Many factors, including genetics and diet, have been implicated in the development of prostate cancer. The Prostate Cancer Prevention Trial found that finasteride reduces the incidence of prostate cancer by 30%. There had been a controversy about this also increasing the risk of more aggressive cancers, but more recent research showed this may not be the case. More than 80% of men will develop prostate cancer by the age of 80. However, in the majority of cases, it will be slow-growing and harmless. In such men, diagnosing prostate cancer is overdiagnosis—the needless identification of a technically aberrant condition that will never harm the patient—and treatment in such men exposes them to all of the adverse effects, with no possibility of extending their lives....
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