Rhesus incompatibility Treatment

Rhesus incompatibility Treatment - erythrocytes are...

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Rhesus incompatibility Treatment All mothers should have be blood typed at the first antenatal visit and repeated at 28 weeks' gestation Anti-D should be given at 28 weeks, and at end of pregnancy (or 40 weeks) intravascular intrauterine blood transfusions if doppler suspects severe anaemia Administration of Anti-D (Rh) Give when foetus is Rh + and Mother is Rh – Additional circumstances: Routinely at 28 wks Gestation Within 72 hours of birth of Rh +va foetus positive With any invasive proceudre in pregnancy Ectopic pregnancy Antepartum haemorrhage Miscarriage Prognosis This is generally preventable and treatable. Prevention Most Rh disease can be prevented by treating the mother during pregnancy or promptly (within 72 hours) after childbirth. The mother has an intramuscular injection of anti-Rh antibodies (Rho(D) Immune Globulin), sold under the brand name RhoGAM. This is done so that the fetal Rhesus D positive
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Unformatted text preview: erythrocytes are destroyed before her immune system can discover them. This is passive immunity and the effect of the immunity will wear off after about 4 to 6 weeks (or longer depending on injected dose) as the anti-Rh antibodies gradually decline to zero in the maternal blood. It is part of modern antenatal care to give all Rhesus D negative pregnant women an anti-RhD IgG immunoglobulin injection at about 28 weeks gestation (with or without a booster at 34 weeks gestation). This reduces the effect of the vast majority of sensitizing events which mostly occur after 28 weeks gestation. Anti-RhD immunoglobulin is also given to non-sensitized Rhesus negative women immediately (within 72 hours - the sooner the better) after potentially sensitizing events that occur earlier in pregnancy....
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Rhesus incompatibility Treatment - erythrocytes are...

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