Thalessemia - Thalessemia Thalassaemia, also known as...

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Unformatted text preview: Thalessemia Thalassaemia, also known as Mediterranean anaemia, is an autosomal recessive blood disorder. Symptoms Children with mild disorder often have no symptoms or only very minor ones. Those children with severe disorder, however usually develop symptoms within the first year of life. Early symptoms include:- • Palid skin • Jaundice • Inability to feed properly • Failure to thrive • Intermittent bouts of fever • Recurrent persistant infections • Bouts of abdominal pain • Dyspnoea As the child ages and the disorder progresses, the bone marrow, spleen and liver increase their activity in an attempt to produce more RBCs to compensate for their anaemia. The following signs are a direct result of this increased activity:- • Thickened bones in the skull and face due to expanding bone marrow • Broadened, thickened bones in the hands • Enlarged spleen • Enlarged liver Causes Adult haemoglobin consists of four protein chains (globins), two alpha and two beta. Normally these Adult haemoglobin consists of four protein chains (globins), two alpha and two beta....
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This note was uploaded on 12/04/2011 for the course ANTHRO 2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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Thalessemia - Thalessemia Thalassaemia, also known as...

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