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Unformatted text preview: heroin readily enter the brain (because of their lipid solubility). This blood-brain barrier is established by the following: Brain capillaries are less permeable than other capillaries because of tight junctions between the endothelial cells in the capillary walls. The basal lamina (secreted by the endothelial cells) that surrounds the brain capillaries decreases capillary permeability. This layer is usually absent in capillaries found elsewhere. Processes from astrocytes (a type of neuroglial cell) cover brain capillaries and are believed to influence capillary permeability in some way....
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- Fall '10