1pp Protein 2011 _Compatibility Mode_

1pp Protein 2011 _Compatibility Mode_ - Protein 2011...

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rotein 2011 Protein 2011
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Outline of Topics • Amino Acids rotein Digestion and Absorption Protein Digestion and Absorption • Requirements through lifecycle • Exercise as it relates to proteins • Creatine
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Essential Amino Acids • Essential amino acids: must obtain from diet TV TILL PM T ryptophan V aline reonine leucine cine sine T hreonine I soleucine L eucine L ysine P henylalanine M ethionine istidine Histidine
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Non-Essential Amino Acids • Non-essential amino acids ietary Dietary – Synthesized in vivo if nitrogen sufficient or from some essential amino acids • Methionine Æ Cysteine • Phenylalanine Æ Tyrosine
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Protein Sources • Exogenous proteins • Animal: meat, poultry, fish, and dairy products • Plant: grains, grain products, legumes and vegetables • Endogenous proteins • Desquamated mucosal cells (~50 g) • Digestive enzymes and glycoproteins (~17 grams) hat’s like 3 proteins shakes per day!!! – That s like 3 proteins shakes per day!!!
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verview of Protein Digestion Overview of Protein Digestion and Absorption
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Protein Digestion • In Stomach – Gastric Parietal Cells release HCl – HCl disrupts the quartenary, tertiary, and secondary ructures structures. – Converts Pepsinogen Æ Pepsin – Pepsin Function – Endopeptidase: cleaves between carboxy group to form large polypeptides, oligopeptides and free amino acids
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Protein Digestion • In small Intestine holecystokinin (CCK) and secretin Cholecystokinin (CCK) and secretin – Synthesized in duodenum in response to acid chyme. – Trigger pancreatic acinar cells to secrete bicarbonate, electrolytes, water and digestive proenzymes. – Proenzymes of importance: » Trypsinogen, Chymotrypsinogen, procarboxypeptidases
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Role of Trypsin in Digestion • Converted from Trypsinogen to Trypsin by Enteropeptidase – Enteropeptidase secreted in duodenum brush border in response to CCK and secretin rypsin converts other zygmogens such as • Trypsin converts other zygmogens such as chymotrypsinogen and rocarboxypeptidases into their active form procarboxypeptidases into their active form.
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nd products of Protein End products of Protein Digestion • Free Amino Acids, dipeptides, and tripeptides hese end products must now be absorbed • These end products must now be absorbed.
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Protein Absorption Amino acids absorbed mainly in proximal small intestine. Paracellular transport Via carriers ost AA transported via Na ependent transporter Most AA transported via Na-dependent transporter Affinity for AA and carrier depends on: » Side chain mass – Bigger sidechain = higher affinity
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1pp Protein 2011 _Compatibility Mode_ - Protein 2011...

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