Elect 3 pp - 1 Fluid & Electrolytes 2011 2011 Fluid •...

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Unformatted text preview: 1 Fluid & Electrolytes 2011 2011 Fluid • Water: ~60% of total body weight • Distribution: Plasma Intracellular 67% Extracellular 33% Plasma Interstitial fluid Lymph Transcellular fluids Fluid Balance • Fluid balance: fluid intake = fluid lost • Fluid intake = ~2,300 mls • Fluid lost: Urine 1,400 mls Sweat 100 mls Feces 200 mls Insensible losses 600 mls Total 2,300 mls Ex: Respiratory Tract, skin, 2 Fluid Balance: Renin-Angiotensin-Aldosterone System Angiotensinogen Juxtaglomerular apparatus (kidney) Angiotensin I Angiotensin II Hypothalamus Antidiuretic hormone (ADH) Water retention Adrenal Aldosterone Sodium Retention Fluid: Adequate Intake • Based on total water = drinking water, beverages, and food M (19 30) 3 7 L/d • Men (19-30): 3.7 L/d • Women (19-30): 2.7 L/d • Infants: • 0-6 mo: 0.7 L/d • 7-12 mo: 0.8 L/d • Immature kidneys: important to consume adequate fluid DRI (2004) Electrolytes • Anions and cations in fluid • Electrical neutrality always maintained • Principal electrolytes: – Sodium – Potassium – Chloride 3 Sodium: Dietary Sources • Major form: sodium chloride (salt) – 40% sodium, 60% chloride – 75% of sodium consumed Added during food processing – Added during food processing: • Canned items, condiments • Pickled foods, snacks • Natural sources: – Milk, meat, eggs, vegetables – ~10% of sodium consumed Sodium: Control • High blood sodium – Aldosterone Renin – Sodium excreted in urine Sodium excreted in urine • Hypothalamus: ADH (vasopressin) – Thirst – Fluid intake • Water reabsorption Sodium: Normal Concentrations • Major extracellular cation – Extracellular concentration = 142 mEq/L • 50% body sodium Intracell lar concentration 10 mEq/L – Intracellular concentration = 10 mEq/L • 10% body sodium • Skeleton • 40% body sodium 4 Sodium: Functions • Membrane transport (see next slide) • Nerve cells • Muscle cells Muscle cells • Water balance – Osmotic pressure – Intracellular K...
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This note was uploaded on 12/09/2011 for the course HUN 4445 taught by Professor Sitren during the Spring '08 term at University of Florida.

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Elect 3 pp - 1 Fluid & Electrolytes 2011 2011 Fluid •...

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