Quiz 7 Spring 2010 Key

Quiz 7 Spring 2010 Key - (b constituent of hemoglobin and...

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HUN 4221 Quiz VII Spring 2010 Form A Multiple Choice (2 pts each) 1. Copper uptake by the enterocyte involves which of the following? (a) Reduction of Cu 2+ to Cu + at the basolateral membrane prior to transport into the portal circulation (b) Chaperone proteins deliver Cu + to organelles and proteins (c) Copper is taken up by the brush border membrane by the receptor ATP7A (d) All of the above (e) None of the above 2. The Divalent Metal Transporter 1 (DMT1) is which of the following? (a) Hepatic protein essential to transport iron into bile (b) Present in the basolateral membrane of the enterocyte for portal blood uptake (c) Not induced by iron deficiency (e) none of the above 3. Which of the following statements correctly describe iron function? (a) cytochrome oxidase contains 2 heme groups and transfer electrons from oxygen
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Unformatted text preview: (b) constituent of hemoglobin and myoglobin for oxygen transfer (c) constituent of cytochrome P450s required for oxidative and reductive transformations (d) all of the above (e) none of the above True or False (1 point) 4. In response to high copper intake the translocation of ATP7B from TGN (trans golgi network) to the bile duct is increased which increases biliary Cu excretion. (a) True (b) False 5. When the body’s iron stores decrease, there is an increase in binding of the iron regulatory protein (IRP) to the iron response element (IRE) in ferritin mRNA which represses translation of the ferritin protein. (a) True (b) False 6. Transferrin saturation is a measure of storage iron. (a) True (b) False 7. Hereditary hemochromatosis is due to a mutation of the gene HFE. (a) True (b) False...
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Quiz 7 Spring 2010 Key - (b constituent of hemoglobin and...

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