Class 18 Cancer Therapy 2011

Class 18 Cancer Therapy 2011 - HUN4445 Cancer Therapy...

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HUN4445 Cancer Therapy Objectives: Discuss the major modalities of cancer therapy Describe the impact of cancer therapy on nutritional status of the cancer patient Discuss the nutritional management of the cancer patient Goals of MNT Prevent or reverse nutrient deficiencies Preserve lean body mass Minimize nutrition-related side effects Maximize quality of life Cancer Treatments 1. Chemotherapy Systemic therapy affects normal and cancerous cells Acts on most actively dividing cells cancer cells, bone marrow, hair follicles, GI tract Classification of Agents Cell cycle-specific agents Antimetabolites Mitotic inhibitors Cell cycle-nonspecific agents Aklylating agents Antitumor antibiotics Hormonal agents Immunotherapy Antitumor Antibiotics Generate O 2 free radicals; cause breaks in DNA Bind to nucleic acids; disrupt DNA helix Doxorubicin (Adriamycin) Hormonal Agents Block hormones that stimulate growth i.e. Glucocorticoids (prednisone, dexamethasone)
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