Genetics Midterm 1 version 1 f08

Genetics Midterm 1 version 1 f08 - Midterm I Version 1...

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Midterm I Version 1 Answer Key Page 1 of 2 - Midterm I Version 1 (Blue) 1. What is the probability that III-11 is heterozygous for the GSDII allele? Answer is e) greater than 80% III-11 is 100% heterozygous 2. What is the probability that their first child will be affected with Glycogen Storage Disease II? Answer is a) 1/48 Calculation: 1/8 Aa X 2/3Aa X ¼ (aa) = 1/48 3. In individuals homozygous for this allele there would be Answer is b) normal levels of transcription of the GSDII gene which would result in the production of a poorly functioning alpha-glycosidase. 4. The above statements illustrate which of the following phenomena? Answer is b) i) epigenetic effects, ii) phenocopy effect and iii) allelic heterogeneity 5. What is the approximate probability that their first child will be phenotypically normal? Answer is e) greater than 60% 6. Which of the following statements best explains the high rate of alpha-glycosidase gene transcription in cardiac and skeletal muscle cells? Answer is d)
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This note was uploaded on 12/09/2011 for the course MBG 2000 taught by Professor C.schisler during the Fall '09 term at University of Guelph.

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Genetics Midterm 1 version 1 f08 - Midterm I Version 1...

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