26 - Wednesday Lecture 26 Announcements 1 This class will...

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Wednesday, October 27, 2010 Lecture 26 Announcements: 1. This class will be moved to Uris Auditorium for the lecture on Friday 10/29/10! 2. Midterm exams will be returned on Friday, along with quiz 6. 3. Series of 3 "prof's info sessions" for medical school will start Friday 11/5 at 2:55pm in Comstock B108. Nov. 5 : the hcec process (writing the personal statement; letters of recommendation); Nov. 12 : what to expect at an interview; Nov. 19 : panel discussion with students who have already had some interviews. 4. HCEC orientation meeting for application to medical school, dental school, etc in 2011: Wed 11/3 at 4:30PM in Warren 231. Monday's lecture: Special role of redox reactions How to calculate Gibbs Function from redox voltages Metabolism: overview and interconnections. Choosing just one biomolecule, galactose, a great many connections are found to other parts of metabolism. Today's lecture: Glycolysis The notion of glycolysis as a "chemical factory" for the cell: . Glucose-6-phosphate can be made into other sugars, and other sugars can be made into G6P. In addition, G1P, released from glycogen, is interconverted with G6P. . Fructose-6-phosphate is the entrance point for other sugars. Also, F6P can be made into amino sugars, which can be made into glycolipids and glycoproteins. From here, glycolsaminoglycans can be made. . Glyceraldehyde-3-phosphate is made into dihydroxyacetone phosphate (DHAP), which can be used for lipid synthesis. . 1,3 bisphosphoglycerate can be made into 2,3 bisphosphoglycerate, which you remember is essential for proper hemoglobin function. . 3-phosphoglycerate is used for serine synthesis. . Phosphoenolpyruvate is used for amino acid synthesis also, as is pyruvate.
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