23 - LECTURE 23 ANNOUNCEMENTS RE 2009 MIDTERM EXAM: WINDOWS...

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LECTURE 23 ANNOUNCEMENTS MIDTERM EXAM THURSDAY NIGHT 7:30 - 10PM. ROOM ASSIGNMENTS: LAST NAME U - Z IN BAKER 219 LAST NAME A - T IN BAKER 200 THE MONDAY LECTURE CARBOHYDRATE BASICS TODAY'S LECTURE CARBOHYDRATE RECOGNITION ROLE INTRO TO BIOENERGETICS CARBOHYDRATE STRUCTURE ENERGY ROLE HAVE A QUESTION DURING THE MIDTERM EXAM?! RE 2009 MIDTERM EXAM: WINDOWS USERS COULD NOT VIEW/DOWNLOAD THE CORRECT KEY TO PROBLEM #13, THE LINEWEAVER-BURK KINETICS GRAPHING PROBLEM. A NEW KEY (PDF FILE) SOLVES THE ISSUE, IS UP NOW ON BLACKBOARD.
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ELECTRON MICROSCOPE IMAGE OF PROTEOGLYCAN 300 nm BIG NEG. CHARGE BIND LOTS OF WATER FULLY EXTENDED, AND NON-INTERACTING WITH OTHER LIKE MOLECULES, i.e. SLIPPERY NOT MADE FROM TEMPLATE: REQUIRE AN ENZYME FOR EACH TYPE OF LINKAGE LUBRICATING FLUID IN JOINTS; MUCOUS COMPLEXITY! GLYCOSAMINOGLYCAN STRUCTURE HYALURONIC ACID LINKER PROTEIN CORE PROTEIN FOUND OUTSIDE OF CELLS; A MAIN COMPONENT OF EXTRACELLULAR MATRIX CHONDROITIN SULFATE KERATAN SULFATE EXCESS CAUSES MITRAL VALVE PROLAPSE!
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PROTEOGLYCANS IN THE EXTRACELLULAR MATRIX (EM) ACTIN FILAMENTS PLASMA MEMBRANE LOOSE MESH OF PROTEOGLYCANS ALLOWS MOLECULES AS LARGE AS PROTEINS (OR EVEN VIRUSES!) TO REACH THE CELL SURFACE INSIDE THE CELL ROLES OF EM: 1. MECH. STRENGTH OF TISSUE/ORGAN; 2. CELLS WITHIN A TISSUE USE IT TO RECOGNIZE EACH OTHER AND DEVELOP SIMILARLY; 3. CELL MOTILITY AND BARRIERS TO MOTILITY DEPEND ON EM (BUT ARE LOST IN METASTASIS)
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23 - LECTURE 23 ANNOUNCEMENTS RE 2009 MIDTERM EXAM: WINDOWS...

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