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basic-bacteriology - PAUL A GULIG PH.D INTRODUCTION TO...

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PAUL A. GULIG, PH.D. INTRODUCTION TO BACTERIOLOGY Lectures January 5, 7, 10, 12, 14 Discussions January 6, 13 Office - R1-250, 392-0050 Lab R1-144, 392-0682 email: [email protected]
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BACTERIA (prokaryotes) VS. EUKARYOTES Cell Structure: Bacteria Eukaryotic Organization Unicellular Unicellular/Multicellular Cell Membrane: transport, motility, transport oxidative phosphorylation, DNA replication Endocytosis/Exocytosis - + Intracellular Membranes: - + (Nucleus, Golgi, Mitochondria, Endoplasmic Reticulum) Cytoskeletal: Microfilaments - + Microtubules - + Cell wall Peptidoglycan - Genetics: Chromosomes 1 (2: Vibrios, Neisseria) >1 Topology Circular Linear Segregation Cell membrane Mitotic spindle Transcription/ coupled in Transcription - nucleus Translation cytoplasm Translation - cytoplasm mRNA capping, - + poly-A Introns (-) + Cistron structure Mono + Polycistronic Monocistronic Ribosome 70S (50S + 30S) 80S (60S + 40S) Genetic Transformation, Meiosis, Zygote fusion Exchange Transduction, Conjugation
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Bacterial structure Small (1-8 microns) Shapes (important for identification and making diagnosis) Others ( vibrios, filamentous, coccobacilli )
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