HW2 - Biophysics Fall 2011 - Homework 2 You are encouraged...

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Biophysics Fall 2011 - Homework 2 You are encouraged to work together, but each of you needs to hand in your own solution. The solution needs to be typed, not handwritten. You should hand in a print out of the solution at the beginning of the class on Friday. Problem 1 : Cellular scales Scale an E. coli cell to the size of a large lecture hall, say 10m x 10m x 30 m and find the corresponding sizes of the following objects. Try to make analogies with familiar household objects. a. What are the diameter and length of genomic DNA; distance separating each base pair, or alternatively the size of a base pair? b. What is the size of a typical small protein? If they fill the hall like a gas, what is the protein spacing? What would be the sizes of the ribosome and RNApolymerase? c. How many pages of a typical novel would it take to spell out the entire genome of E. coli? Assuming the information content of the genome is comprised mostly in the genes, how many pages of a typical novel would the information be comparable to? [You may
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HW2 - Biophysics Fall 2011 - Homework 2 You are encouraged...

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