LEC5_GLOBAL_2011

LEC5_GLOBAL_2011 - GlobalaspectsofHIV/AIDS November15,2011...

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Global aspects of HIV/AIDS   November 15, 2011
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Outline for today’s class 2)  Possible explanation(s) for  HIV in sub-Saharan Africa 3)  Distribution of HIV by gender  ( disparity in sub-Saharan Africa ) 4)  Financing HAART ( demonstration of political will ) 6)  PBS segment 
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A global view of HIV infection 33 million people [ 30–36 million ] living with HIV, 2007
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People Living with HIV, by Region   Sub-Saharan Africa 63% North Africa and Middle East 1% South and South- East Asia 20% Latin America 4% Caribbean 1% Eastern Europe and Central Asia 4% Oceania <1% East Asia 2% North America 3% Western and Central Europe 2% Source: UNAIDS , 2006 Report on the Global AIDS Epidemic , 2006.
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Global Transmission of HIV Developed countries   (e.g. United States) Started primarily among MSM Moved into drug-using populations,  eventually leading to transmission via heterosexual sex Sub-Saharan Africa and Latin America   Transmission attributed to heterosexual sex started primarily among intravenous drug users Male drug users subsequently infected female sex workers Prostitution contributed to ongoing heterosexual transmission e.g. military recruits in Thailand/Cambodia
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0 10000 20000 30000 40000 50000 60000 70000 80000 90000 N o f c a s e s 1987 1989 1991 1993 1995 1997 1999 2001 2003 2005 IVDU Sexual Newly reported HIV cases in Russia
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Why is HIV prevalent in sub-Saharan Africa? Large no. of sexual partners This theory has been  debunked ; studies demonstrate equal no. of partners in  Africa and other continents High-risk, Low-risk Mixing Theory Prostitutes   migrant workers/truckers/itinerant workers   general population Long-term concurrent sexual relations Polygamy ‘Transactional’  sexual relations Not considered a form of prostitution; rather, women expect gifts of cash or  consumer goods from boyfriends Could actually be riskier than prostitution  (compare to brothels in Asia)
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Importance of partner sequences Martina Morris, PhD (2007)
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Importance of concurrency / networks Martina Morris, PhD (2007) Explains how the 1 faithful partner  can become infected
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This note was uploaded on 12/13/2011 for the course BIOSCI 45 taught by Professor Staff during the Fall '11 term at UC Irvine.

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LEC5_GLOBAL_2011 - GlobalaspectsofHIV/AIDS November15,2011...

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