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Lec+24+2011+NEW

Lec+24+2011+NEW - Reading Chapter 18 366-373-447 24-1...

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Unformatted text preview: Reading Chapter 18: 366-373 Chapter 21 445-447. 24-1 Lecture 24: The Genetic Basis of Development Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved Friday 11/18/11 How do you go from zygote to mature individual? Human zygote 24-2 Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved • Gametes are haploid cells formed during meiosis • Gametes fuse at fertilization to form a single diploid cell (zygote) • Zygote divides by mitosis to form 2, 4, 8 ….. Millions to billions of cells that makes up the organism Four processes transform the zygote into the adult 1. Proliferation: Cell division 2. Differentiation: Different genes are turned on in different cells 3. Morphogenesis: Cells move to the appropriate locations and the organism ’s shape is formed 4. Apoptosis: Regulated cell death 24-3 O’Dowd and Warrior, UCI - Copyright: All rights reserved Two prominent theories about development - preformation and epigenesis • Preformation theory suggested that all structures exist from the very beginning, they just get larger. 24-3 O’Dowd and Warrior, UCI - Copyright: All rights reserved • Epigenesis, on the other hand, argues that new structures arise progressively - by going through a series of different stages. 24-3 O’Dowd and Warrior, UCI - Copyright: All rights reserved (a) Cytoplasmic determinants in the egg Two different cytoplasmic determinants Unfertilized egg cell Sperm Fertilization Zygote Mitotic cell division...
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Lec+24+2011+NEW - Reading Chapter 18 366-373-447 24-1...

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