Lec23+2011 - Lecture 23: Recombinant DNA Technology Wed...

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Lecture 23: Recombinant DNA Technology Wed 11/16/11 Reading Chapter 20 Pgs 396-408 23-1 Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved
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Type 1 Diabetes Inheritance: Polygenic disease Environmental factors influence expression Symptoms High blood glucose due to defective insulin production Blood glucose level rises Insulin B-cell in pancreas Body cells take up glucose Blood glucose levels fall Blood glucose (90 mg/100 ml) 23-2 Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved X
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Treatment: Injections of exogenous Insulin Before 1982: insulin purified from animals (pig) 1982: Humulin: synthetic human insulin marketed Produced by recombinant DNA technology More effective Fewer side effects 23-3 Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved
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DNA cloning in bacteria Ability to combine genes from different sources into a single DNA molecule 23-4 Bio 93, O’Dowd and Warrior, UCI - Copyright: All rights reserved
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This note was uploaded on 12/13/2011 for the course BIOSCI d103 taught by Professor Staff during the Fall '11 term at UC Irvine.

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Lec23+2011 - Lecture 23: Recombinant DNA Technology Wed...

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