{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

PS1 - nerve cell crosses the synaptic cleft and binds to a...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Problem set 1: 1. Hydrophobic amino acids tend to group themselves in the cores of proteins a) What interaction is mediating this? Explain how it occurs. b) List four amino acids you would expect to find in the core of proteins. Include structures and abbreviations. c) What is the rational that the R groups of the amino acids you listed above are of different shapes? 2. Given the following reaction for which the pK a is 6.86 H 2 PO 4 - H + + HPO 4 2- a) What would the molar ratio of [H 2 PO 4 - ] to [HPO 4 2- ] be in order to have a pH of 7.2? b) Define the term buffer. Would this be a good buffer system at pH 7.2? Why or why not? 3. The amino acid glutamate is also used as a neurotransmitter. It is released from one
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: nerve cell, crosses the synaptic cleft and binds to a glutamate receptor on a second nerve cell, triggering a response. a) Draw the structure of glutamate b) In order for glutamate to interact with the receptor, it must form multiple interactions within the binding site. For each of the functional groups on glutamate, indicate which groups of amino acids (including a representative example) could be present in the receptor to bind specifically glutamate. Make sure to include two different types of interactions. c) Would you expect to see a large number of higher energy interactions? Textbook problems: Chapter 2: Q. 3, 5, 6, 7, 8, 9, 13. Pages 63-64...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern