BIOL 200 (Section 921)
Lecture # 1
June 15, 2009
Essential Cell Biology (ECB) 2
Chap 2, Chap 5
, pages 169-177
Background Study Material
: Study Panels 2-1, 2-2, 2-3, 2-4, 2-5, 2-6, 2-7 (pages 66-79).
1-6, 1-7, 1-9, 1-10, 1-12, 1-18.
1.Make a diagram relating the relative size of a typical nucleus, mitochondrion, a
bacterium and a ribosome.
2. Practice to identify the cell organelles in electron micrographs of a variety of cell types using the Image
Be able to critically define cells and organelles
Know the major classes of eukaryotic cell organelles and their functions.
Develop a general feel for the flow of information and the flow of material in cells.
Know the different types of microscopy and their functions
Know the mechanism and key reactions of synthesis of macromolecules
Know the different forces that stabilize the DNA structure
I. CELL ORGANIZATION - Structure & Function
Cells and organelles
are biological structures, bounded by membrane
that are capable of carrying out essential life
processes such that they can maintain a stable internal environment
with concentrations of molecules and
ions that differ from those outside, can transform and assimilate material
, and reproduce
Single cells can be an individual=unicellular organism
Cells can be organized into communities=either as colonies of individuals or multicellular
organisms. In multicellular organisms, cells specialize or "differentiate". All cells of an organism
contain same DNA but differential gene expression leads to very different cell structures.
Cells are divided into two fundamental types: (Panel 1-2: bacterial cell vs. 2 types of eukaryotes
(animal and plants).
1. Eukaryotes (true nucleus)-typical of multicellular organisms, contain nuclei and subcellular
compartments surrounded by cytoplasm. Can be unicellular (e.g. protozoans)
2. Prokaryotes (before nucleus)-bacteria, nucleic acids in cytoplasm; Prokaryotic cell – no organelles, no