10-11-11 - 10/11/2011 An Adrenaline Rush Through cAMP Fight...

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10/11/2011 An Adrenaline Rush Through cAMP Fight or Flight: o Noticeable Effects: Pupils Dilate Mouth goes dry Neck and Shoulder Muscles tense Heart pumps faster Chest pains Palpitations Sweating Muscles tense for action Hyperventilation Oxygen needed for muscles o Hidden Effects: Brain gets body ready for action Adrenaline released Blood Pressure rises Liver releases glucose to provide energy for muscles Digestion slows or ceases Sphincters close, then relax Cortisol released (Deppresses the immune system) Earl Sutherland, 1971 – Identified cAMP as being generated in Liver cells after exposure to adrenaline o Demonstrated that cAMP added to liver cells caused the same response as adrenaline. cAMP was sufficient in mediating the adrenaline response. Could have proved that it was essential by inhibiting it’s production in an experiment. o
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This note was uploaded on 12/13/2011 for the course BIO 362 taught by Professor Walikarzai during the Spring '10 term at SUNY Stony Brook.

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10-11-11 - 10/11/2011 An Adrenaline Rush Through cAMP Fight...

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