5.+Kinetoplastids+African+Trypanosomes

5.+Kinetoplastids+African+Trypanosomes - TheKinetoplastids...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
The Kinetoplastids Leishmania spp. Trypanosoma spp. *
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
African Trypanosomiasis Trypanosoma brucei gambiense (Dutton 1902) Trypanosoma brucei rhodesiense African Sleeping Sickness
Background image of page 2
Terms from the documentary- Sleeping Sickness Democratic republic of the Congo  (DRC; aka Zaire)  3rd largest African country (area)  >68 million people Second Congo War began in 1998:  7 foreign armies  fighting continues in east  deadliest conflict since World War II  ~5.4 million people killed Citizens of the DRC are among the poorest in the world,  lowest per  capita GDP ($171./year) ~50% of deaths are children under age 5.  Lumbar puncture  = spinal tap (cerebrospinal fluid) Melarsoprol – arsenic containing drug Eflornithine, Nifurtimox: other anti-typanosome drugs Combination therapy: giving two drugs together Nifurtimox
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Kill or Cure: Sleeping Sickness  Season 4 Episode 6 Experts thought Sleeping Sickness had been  destroyed decades ago. But it's back with a  vengeance. Kill or Cure journeys to the Democratic  Republic of Congo to see the devastation Sleeping  Sickness causes. Without treatment sufferers face  almost certain death. Whole communities have been  crippled by the disease. Mobile teams are in the field  carrying out rapid blood tests and lumber punctures  to identify and beat the disease. http://www.rockhopper.tv/programmes/3/
Background image of page 4
only in sub-Saharan Africa  lives in bloodstream of mammals  cattle disease : “nagana” ( Trypanosoma brucei   brucei ) human disease : “Africans sleeping sickness” Trypanosoma brucei gambiense  (1902) Trypanosoma brucei rhodesiense  (1910)   2005: 450,000 cases throughout sub-Saharan Africa 60 million people are at risk tsetse fly vector recently classified as a re-emerging infection:  extensive forced migration caused by civil turmoil  breakdown of control measures against vector  African Trypanosomiasis
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
•infection through a broad region of equitorial Africa  ( regions south of equator ) T. gambiense Cameroon,  Benin, Central African Republic, Gabon, Ghana, Guinea, Ivory Coast,  Congo ) •the domestic pig  is only important reservoir for  gambiense T. rhodesiense  mainly found in east Africa ( Burundi, Botswana, Congo, Ethiopia, Kenya, Mozambique, Rwanda,  ) reservoirs for  rhodesiense   gambiense  versus  rhodesiense
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 20

5.+Kinetoplastids+African+Trypanosomes - TheKinetoplastids...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online