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Worksheet+3+-+Answer+Key - Bio 93 Worksheet 3 Lecture 6 and...

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Bio 93 Pooja Patel Worksheet 3 – Lecture 6 and 7 [email protected] Lecture 6: Cell Communication Cell Signaling Three stages 1. Reception a. Signal (ligand) binds to receptor induces change in location and/or shape b. Receptors b.i. Plasma membrane proteins b.i.1. Ligands are secreted, water soluble, membrane-bound G - protein-linked receptor (ligands are usually hormones or neurotransmitters) Tyrosine kinase receptor (ligands include growth factors) Ligand-gated ion channels (neurotransmitters are ligands)
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Bio 93 Pooja Patel Worksheet 3 – Lecture 6 and 7 [email protected] b.ii. Cytoplasmic or nuclear proteins b.ii.1. Ligands are lipid soluble Intracellular Receptors o Ligands are membrane permeant, sometimes steroid hormones o Receptor in cytosol or nucleus 2. Transduction 3. Response Four types of signaling 1. Paracrine and Synaptic Signaling a. Secreted signals that act locally (e.g. growth factors, neurotransmitters)
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Bio 93 Pooja Patel Worksheet 3 – Lecture 6 and 7 [email protected] 2.
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