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Unformatted text preview: o Point Mutations Base pair insertion or deletion Insertions and deletions can also produce frameshift mutations Bio 93 Pooja Patel Worksheet 11 Lecture 22 email@example.com Regulation of Gene Expression 1. Only a small fraction of genes in the genome are expressed in any given cell 2. Gene expression is primarily regulated by transcription 3. Gene expression is also regulated by steps such as a. RNA processing b. RNA stability/degradation c. RNA translation d. Protein modification e. Protein stability/degradation Regulation of Transcription o TATA and promoter is required to attract RNA polymerase o Enhancers and transcription factors are specific to each other Alternative Splicing o Generating different proteins from the same gene o When introns are spliced out, some exons are kept and others are not Regulation by microRNA (miRNA) o Complementary to mRNA o Binds to mRNA o mRNA is degraded OR translation is blocked...
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This note was uploaded on 12/13/2011 for the course BIOSCI 93 taught by Professor Staff during the Fall '11 term at UC Irvine.
- Fall '11