Linkage-mapping-etc

Linkage-mapping-etc - D137 JLMarsh Aassigning linkage If...

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D137 JLMarsh Aassigning linkage. If two markers are NOT independent, they are linked. If they are independent, they are either unlinked or far from each other on a long chromosome. Approach = analyze 2 loci at a time. Here we can deduce the parental linkage relationships as (Tbs) & (tBS) Observe Note the preponderance of parental types for TB Overall TB TS BS Tbs 25 Tb 50 Ts 25 bs 25 TbS 25 " TS 25 bS 25 Note: 1:1:1:1 ratio = independent tBS 25 tB 50 tS 25 BS 25 tBs 25 " ts 25 Bs 25 TBs 0 TB 0 TBS 0 tbS 0 tb 0 tbs 0 In this example, T & B are NOT independent and thus are linked. S is independent of both T & B so the linkage is Tb/tB; S/s
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D137 JLMarsh 3 POINT MAPPING note: I list here ONLYthe genetype coming from the female where all the exchange events are occurring. None occur in the male and all of the genotypes shown above are over either /Y or /abc e.g. a++/Y or a++/abc. Because of the genotypye of the father here, the alleles coming from the female can be deduced. 5 EASY STEPS TO 3 POINT MAPPING
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Linkage-mapping-etc - D137 JLMarsh Aassigning linkage If...

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