Practice+Midterm+11

Practice+Midterm+11 - Bio D137 Human and Eukaryotic...

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Bio D137 Human and Eukaryotic Genetics J.L.Marsh F'11 Practice MidTerm questions Name/student ID:_______________ 1 1) Consider chromosome 13 of humans. Assume in one marriage the parents are 13 a 13 b (male) and 13 c 13 d (female), where a, b, c, and d stand for cytologically detectable polymorphic alleles of an enzyme that maps on chromosome 13. Fetuses of the following types are produced: (42A stands for the rest of the autosomes.) a] 42A + 13 a 13 c 13 c + XY b] (42A + 13 d + XX); (42A + 13 a 13 d + XX); (42A + 13 a 13 a 13 d + XX) For each fetus, describe with carefully labeled diagrams the events that gave rise to the condition. Points are given for the diagram demonstrating what is going on. State in which individuals the events took place. C] Would you expect one of these children to be less severely affected than the other and if so, which one and why?
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Bio D137 Human and Eukaryotic Genetics J.L.Marsh F'11 Practice MidTerm questions Name/student ID:_______________ 2 2] Keloids are scars that proliferate beyond the boundaries of the original injury. Keloids can continue to grow indefinitely and no satisfactory treatment has been identified. Etiological evidence has pointed to a possible genetic predisposition in humans. However, it is unclear what the inheritance patterns of this disease are. Various studies have provided conflicting evidence, supporting an autosomal recessive pattern, an autosomal dominant pattern, or an
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Practice+Midterm+11 - Bio D137 Human and Eukaryotic...

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