PS4_F11 - Bio D137 Human and Eukaryotic Genetics Prob Set 4...

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Bio D137 Human and Eukaryotic Genetics J.L.Marsh F'11 Prob Set 4 due Oct, 18 1 1] Black body color, scarlet eye color and hooked bristles are three autosomal recessive mutations in Drosophila governed by the genes b , st , hk respectively. The results of a trihybrid testcross are given below: 245 black 239 black, scarlet 13 black, hook 12 black, hook, scarlet 228 hook 233 hook, scarlet 16 scarlet 14 wild type A]What would the genotype of the tester be? Why? B]From the data deduce the linkage relationships of these genes. Be sure to figure out the map distances between linked genes. C]Can you deduce the parental linkage relationships of the trihybrid (triple heterozygote) parent (ie what alleles were contributed by the father and what alleles were contributed by the mother? - ie coupling and repulsion). Please indicate the parental genotype. Hint : Solve the problem by first examining pairwise segregation in order to determine the parental linkage relationships (eg ask who is independent of whom?). 2. You have two pure breeding strains of rabbits. One strain has black spots and straight ears (bbSS). The other strain is pure black (no spots) with floppy ears (BBss). Your boss wants you to find out whether the two genes responsible for these traits assort independently or are linked. You cross the two pure
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PS4_F11 - Bio D137 Human and Eukaryotic Genetics Prob Set 4...

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