Genetics

Genetics - The Rise of the Science of Genetics Gregor...

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Genetics: Genome All living organism use similar genetic systems Genome is a complete set of genetics instructions for any organism All genomes are encoded in nucleic acids- either DNA or RNA The coding system is common to all life; with rare exceptions, the code words are identical Model Genetic Organisms Model organisms are organisms with characteristics that make them useful for genetics analysis: Large progeny Adaptability to a lab environment Ability to be housed and propagate inexpensively Short generation time The zebrafish – instrumental in helping to identify genes encoding pigmentation differences among humans SLC24A5 gene (solute carrier family 24 member 5; also known as NCKX5) – responsible for a 24%- 38% of the differences in pigmentation between Africans and Europeans The use of genetics by humans began with the domestication of plants and animals Preformationism (17 th and 18 th century) A tiny miniature adult, a homunculus , exists inside egg or sperm
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Unformatted text preview: The Rise of the Science of Genetics Gregor Mendel (1822 1884) Cell theory (1839) Schleiden and Schwann All life compose of cells, cells arise only from pre-existing cells Walther Flemming (1843 -1905) Observed the division of chromosomes and published description of mitosis Nucleus contains hereditary information Germ-plasm theory Proposed by August Weismann (1834-1914) DNA structure proposed in 1953 Watson, Crick, Wilkins, Franklin 1973 -First recombinant DNA experiment 1977- DNA sequencing (Gilbert and Sanger) 1990- Gene therapy 1995- Human genome project was launched completed in 2003 Germ-plasm theory Proposed by August Weismann (1834-1914) DNA structure proposed in 1953 Watson, Crick, Wilkins, Franklin 1973 -First recombinant DNA experiment 1977- DNA sequencing (Gilbert and Sanger) 1990- Gene therapy 1995- Human genome project was launched completed in 2003...
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Genetics - The Rise of the Science of Genetics Gregor...

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