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Ch11_Test_File - Chapter 11 DNA and Its Role in Heredity...

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Chapter 11: DNA and Its Role in Heredity TEST FILE QUESTIONS Multiple Choice 1. In the 1920s, circumstantial evidence indicated that DNA was the genetic material. Which of the following experiments led to the acceptance of this hypothesis? a. Griffith’s experiments with Streptococcus pneumoniae b. Avery, MacLeod, and McCarty’s work with isolating the transforming principle c. Hershey and Chase’s experiments with viruses and radioisotopes d. Franklin’s X-ray crystallography e. a, b, and c Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? p. 233 2. In Griffith’s experiments, when heat-killed S strain pneumococci were injected into a mouse along with live R strain pneumococci, a. DNA from the live R was taken up by the heat-killed S, converting the latter to R and killing the mouse. b. DNA from the heat-killed S was taken up by the live R, converting the latter to S and killing the mouse. c. proteins released from the heat-killed S killed the mouse. d. RNA from the heat-killed S was translated into proteins that killed the mouse. e. there was no result. Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? p. 234 3. Experiments designed to identify the transforming principle were based on a. purifying each of the macromolecule types from a cell-free extract. b. removing each of the macromolecules from a cell, then testing its type. c. selectively destroying the different macromolecules in a cell-free extract. d. Both a and b e. Both a and c Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? p. 234 4. Griffith’s experiment with pneumococcus demonstrated that Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? p. 234 5. Griffith was able to distinguish the two strains of pneumococcus by means of
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Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? p. 234 6. In order to show that DNA is the “transforming principle,” Avery, MacLeod, and McCarty showed that DNA could transform nonvirulent strains of pneumococcus. Their hypothesis was strengthened by their demonstration that Textbook Reference: 11.1 What Is the Evidence that the Gene is DNA? pp. 234–235
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