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Unformatted text preview: Skeletal Muscle PhysiologY Structure of Sketetal Muscle Cells (Fibers): 1. myofibrils 2. multi-nucleate 3. striated 4. sarcolernma : Plasma nre'nbrans (endomYsium) 5. sareoplasm: glycogen and myoglobin 6. cylindrical & elongated 7. A=10 - 100 pm 8. other organelles 9. Sarcoplasmic Reticulum: SER 10. T-tubules (sarcolernrna) IVrvofibril ,' ,",n o'c[ 11r '\,+" (a."' t".."L-l[*< to^ (- > l,t.tt*o1r*. I . rnat<iirip muscle fiber (100s - 1000s) 2. rodlike 3. parallel arrangement 4. extend length 5. packed 6. bands A:dark ( n L<*""'d * r \r. H zone: lighter stripe \lu'" $.q h--tdc\'Yt ) M line: bisects H (holds adjacent thick filaments together) I = light Zhne: bisects I (anchors adjacent thin filaments) 7. chains of sarcomeres Sarcomere 1. functional unit of \\\tL; e\a t t:t[xl, t \to ' 2. myofilaments I 3. between two Z lines Ulvofilaments A) Thick A Myosin .flriG *, or.'\ t'.\\\tE\"-"\\h ( \..t A \nr""'l Double headed golf club: a) heads (globular): face out, in opposite directions, studded appearance, cross bridges, ATP binding sites, ATPase b) tails: central, smooth, rod like B) Thrn :r' ' J Across I and into A Zline 1. actin - double helix, active sites (myosrn binding siles) -t ,' . 2. tropomyosin - blocks actrn's active site N"n-I )''o'tt ut t t 5 3. troponin - another regulatory protein CROSS SECTION through A Intracellular Tubuleq...
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This note was uploaded on 12/14/2011 for the course PHYS 345 taught by Professor Dr.abdirkin during the Spring '11 term at St. Thomas FL.
- Spring '11