What Freud failed to emphasize sufficiently, however, was the anesthetic effect of cocaine on mucous membranes such as the nose and mouth. A colleague of his, Dr. Kohler, performed experiments while Freud was visiting his fiancé that showed that cocaine could be used to anesthetize the eye for the purposes of eye surgery. Since there was no other effective way to do this at the time, Kohler's discovery was a major one, and Freud deeply regretted not making the discovery himself. After this disappointment, Freud continued his research with cocaine, eventually publishing two more papers. The first one was slightly more subdued in its praise than "Über Coca" had been, and the third one was even more skeptical. Freud frequently used cocaine himself to deal with minor aches and pains, and he recommended it enthusiastically to friends and acquaintances, even going sending Martha Bernays
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