mehta5455 - Lipid Transport and Storage Medical...

Info iconThis preview shows pages 1–28. Sign up to view the full content.

View Full Document Right Arrow Icon
Lipid Transport and Storage Medical Biochemistry Lectures #54 and #55
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 12
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 14
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 16
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 18
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 20
Background image of page 21

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 22
Background image of page 23

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 24
CLINICAL ASPECTS: 1.  Imbalance in the rate of  triacylglycerol formation and export  causes fatty liver.   • Accumulation  of  lipid as triacylglycerol  in  the liver causes cirrhosis and impaired liver  function.
Background image of page 25

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Fatty liver falls into two categories: a.  Raised levels of plasma free fatty acids resulting from  mobilization  of  fat  from  adipose  tissue  or  from  the  hydrolysis  of  lipoprotein  triacylglycerol  by  lipoprotein  lipase in extrahepatic tissues.  • Increasing amounts of free fatty acids are taken up by the  liver and esterified.  The production of VLDL does not  keep  pace  with  the  influx  of  free  fatty  acids,  allowing  triacylglycerol to accumulate, causing fatty liver.  • During starvation, quantity of triacylglycerol in the liver  is increased, and ability to secret VLDL is impaired.   This may be due to low levels of insulin.
Background image of page 26
b. Due  to  a  metabolic  block  in  the  production  of 
Background image of page 27

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 28
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 35

mehta5455 - Lipid Transport and Storage Medical...

This preview shows document pages 1 - 28. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online