LEC21 - Interdisciplinary School of Health Sciences Faculty...

Info icon This preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
Interdisciplinary School of Health Sciences Faculty of Health Sciences University of Ottawa HSS 2101 B Health Problems (3 credits) Professor: Dr. Karen Phillips Office Hours: Templeton Room 215, Tuesdays 1:00-2:20pm After end of classes office hours will be moved to different date.
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Date Topic Tuesday, March 1 14. Diseases/Disorders of the Gastrointestinal Tract Chapter 9 Friday, March 4 15. Cardiovascular Disease I Chapter 6 Tuesday, March 8 16. Cardiovascular Disease II Chapter 7 Friday, March 11 17. Respiratory Disease Chapter 8 Tuesday, March 15 18. Pathology of the Reproductive System- Chapter 11 (Assignment Due 5%) Friday, March 18 19. Diseases Associated with Pregnancy Chapter 12 Tuesday, March 22 20. Renal Pathology Chapter 10 CLASS EVAL. Friday, March 25 21. Diabetes Chapter 12 Tuesday, March 29 22. Diseases of the Endocrine System Chapter 12 Friday, April 1 23. Pathology of the Nervous System I Chapter 13 Tuesday, April 5 24. Pathology of the Nervous System II Chapter 13 Friday, April 8 REVIEW Final Exam Lectures 14-24; 45%
Image of page 2
Hormones of the Pancreas several hundred thousand clusters of cells- islets of Langerhans four types of cells: beta cells, which secrete insulin alpha cells, which secrete glucagon; delta cells, which secrete somatostatin, and gamma cells, which secrete a polypeptide of unknown function
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
As food is digested glucose enters the bloodstream insulin released glucose taken up to muscle, liver, fat Diabetic patients- have high blood glucose Blood Glucose Regulation Blood Glucose Regulation
Image of page 4
Blood Glucose Regulation Blood Glucose Regulation
Image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Beta Cells produce insulin –required for glucose homeostasis Contain glut2 transporters which transport glucose from blood into beta cell Glucose triggers intracellular events which result in insulin secretion Trigger for insulin secretion from beta cells: rising level of circulating glucose ("blood sugar").
Image of page 6
Insulin Peptide hormone Synthesized as inactive pro- hormone binds insulin receptor: transmembrane protein receptor expressed by responding cells (liver, skeletal muscle, fat cells)
Image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Liver Muscle Adipose tissue Insulin + glycogen synthesis + glucose uptake + glucose uptake + glycolysis + amino acid uptake + free fatty acid uptake - glycogenolysis - proteolysis - lipolysis - gluconeogenesis - ketogenesis Glucagon + glycogenolysis minimal action minimal action + gluconeogenesis + ketogenesis Insulin and Glucagon
Image of page 8
Major types of diabetes: Diabetes Mellitus 1.Type I diabetes (insulin dependent diabetes mellitus) 2.Type II diabetes (insulin in dependent or insulin resistant diabetes mellitus ) 3.Gestational diabetes endocrine disorder, signs and symptoms: Glucose in urine Increased volume of urine (osmotic effects) increased blood glucose levels diabetes insipidus : different disease; produces large volume of urine ADH deficiency, unrelated to glucose homeostasis
Image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Diabetes Mellitus Diabetes Mellitus
Image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern