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Abnormalities of the Sex Chromosomes

Abnormalities of the Sex Chromosomes - Additional X...

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Abnormalities of the Sex Chromosomes Turner Syndrome - XO Characteristics of Turner syndrome include the following: Sexually underdeveloped Short stature Folds of skin on the back of the neck Wide-spaced nipples Narrow aorta Pigmented moles 97% die before birth Malformed elbows Infertile Normal Intelligence The incidence of Turner syndrome is 1 in 2000 female births. Turner syndrome individuals that are treated with hormones lead fairly normal lives. XXX - Triple-X Syndrome (also XXXX and XXXXX) Triple-X individuals are tall and thin and have menstrual irregularities. Their IQ is in the normal range but it is slightly reduced. The incidence of Triple-X Syndrome is 1 in 1,500 female births.
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Unformatted text preview: Additional X chromosomes are associated with an increased mental handicap. XXY - Klinefelter Syndrome (also XXXY) Males with two or more X chromosomes have Klinefelter Syndrome. The incidence of Klinefelter Syndrome is 1 in 1000 male births. Symptoms include reduced sexual maturity and secondary sexual characteristics, breast swelling (gynecomastia), and infertility. Klinefelter males are slow to learn and individuals with additional X’s (XXXY) may be mentally retarded. XYY - Jacob Syndrome Most XYY males are normal and are unaware of an additional chromosome. XYY males tend to be tall and may have speech and reading problems....
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