Formation of Acetyl CoA

Formation of Acetyl CoA - Two acetyl CoA molecules are...

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Formation of Acetyl CoA Pyruvate produced by glycolysis (see above) enters the mitochondrion and is converted to acetyl CoA by the reaction below. The remainder of the reactions of cellular respiration occur in the mitochondrion . pyruvate (C 3 ) acetyl CoA (C 2 ) + CO 2 During this step, NADH is produced from NAD + + 2H (oxidation). This step must occur twice for each glucose molecule because each glucose molecule produces two pyruvate molecules in glycolysis (above). The two-carbon compound produced is attached to Coenzyme A to produce acetyl CoA. Krebs Cycle The Krebs cycle can be summarized by either of the diagrams below. The diagram below occurs twice, once for each acetyl CoA. When acetyl CoA attaches to a C 4 molecule in the Krebs cycle, the Coenzyme A is released.
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Unformatted text preview: Two acetyl CoA molecules are consumed to produce 4 CO 2 , 2ATP, 6 NADH and 2 FADH 2 . The ATP molecules are produced by substrate-level phosphorylation. The diagram below also summarizes the Krebs Cycle. Electron Transport and Oxidative Phosphorylation Mitochondrion structure The inner membrane forms folds called cristae . These folds contain the carriers of the electron transport system. Acetyl CoA formation and the Krebs cycle occur in the inner space called the matrix. The space outside the inner membrane is the intermembrane space . The electron transport system pumps hydrogen ions (H + ) into this space for oxidative phosphorylation....
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This note was uploaded on 12/15/2011 for the course BIO BSC1010 taught by Professor Gwenhauner during the Fall '10 term at Broward College.

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Formation of Acetyl CoA - Two acetyl CoA molecules are...

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