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Growth Factors - M-Cyclin M-Kinase combines with M-cyclin...

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Growth Factors Growth factors are molecules that stimulate nearby cells to divide by promoting the binding of cyclin to kinase. Under normal conditions, cyclin combines with kinase only when growth factors are present. For example, damaged tissue releases growth factors to stimulate cell division needed to repair the tissue. S-Cyclin S-Kinase combines with S-cyclin and the resulting active complex stimulates DNA replication. The "S" in S-kinase and S-cyclin refers to DNA synthesis . Enzymes triggered by the active kinase-cyclin complex then destroy the S-cyclin.
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Unformatted text preview: M-Cyclin M-Kinase combines with M-cyclin and the active complex initiates several mitotic events: 1. chromosome condensation (coiling) 2. nuclear membrane disintegration 3. the synthesis of the spindle apparatus The active kinase-cyclin complex also activates enzymes that destroy the M-cyclin. Prokaryotes Prokaryotic cells do not undergo mitosis. When the cell divides, the circular chromosome replicates itself (DNA synthesis) and the cell pinches into two. This process is called binary fission ....
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