Prenatal Diagnosis

Prenatal Diagnosis - cultured on a laboratory culture dish...

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Prenatal Diagnosis The techniques listed below enable physicians to diagnose many kinds of genetic abnormalities by examining some of the cells from the developing fetus. Amniocentesis The fetus is surrounded by a layer of liquid called amniotic fluid. Amniocentesis is a technique in which a sample of amniotic fluid is removed and cells that it contains are grown on a culture dish. Because these cells are of fetal origin, any chromosomal abnormalities present in the fetus will also be present in the cells. In addition to chromosomal analysis, a number of biochemical tests can be done on the fluid to determine if any problems exist. Amniocentesis cannot be done until the 14th to 16th week of pregnancy. Cells must then be
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Unformatted text preview: cultured on a laboratory culture dish for 2 weeks to obtain sufficient numbers of cells. The risk of inducing a spontaneous abortion by this procedure is 0.5 to 1% above the background rate of spontaneous abortion. Chorionic Villi Sampling Chorionic villi sampling is a procedure in which a small amount of the placenta is removed. It is normally done during the 10th to 12th week but it can be done as early as the 5th week of pregnancy. Karyotype analysis can be performed on these cells immediately after sampling. Although Chorionic villi sampling can be performed earlier in the pregnancy than amniocentesis, the risk of inducing a spontaneous abortion is 1 to 2% higher than the background rate....
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