The transforming material is DNA

The transforming material is DNA - The transforming...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
The transforming material is DNA - Oswald Avery, Colin MacLeod, and Maclyn McCarty, 1944 Prior to the work of Avery, MacLeod, and McCarty, the genetic material was thought to be protein. Avery, MacLeod, and McCarty worked to determine what the transforming substance was in Griffith's experiment (above). They purified chemicals from the heat-killed S cells to see which ones could transform live R cells into S cells. They discovered that DNA alone from S bacteria caused R bacteria to become transformed. They also discovered that protein-digesting enzymes (proteases) and RNA-digesting enzymes (RNAse) did not affect transformation, so the transforming substance was not a protein or RNA. Digestion with DNase did inhibit transformation, so DNA caused transformation. They concluded that DNA is the hereditary material, but not all biologists were convinced. More Evidence: The Genetic Material is DNA - Alfred D. Hershey and Martha Chase, 1952 Hershey and Chase worked with viruses that infect bacteria called bacteriophages. The bacteriophage becomes attached to the bacteria and its genetic material then enters the
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 12/15/2011 for the course BIO BSC1010 taught by Professor Gwenhauner during the Fall '10 term at Broward College.

Page1 / 2

The transforming material is DNA - The transforming...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online