Transgenic Animals

Transgenic Animals - cloned This process has been done by...

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Transgenic Animals Pharmaceutical companies are developing techniques to produce chemicals using animals. The drug is produced in the milk of females. For example, goats have been developed to produce antithrombin III, used to prevent blood clots. Clinical trials of this drug will begin soon. Lactoferrin is added to infant formula to transport iron and to prevent bacterial infections in the gastrointestinal tract. A transgenic bull has been produced that carries a gene for the production of human lactoferrin. Females will produce milk with lactoferrin. A sheep has been bioengineered to produce tPA (tissue plasminogen activator) in her milk. Tisue plasminogen activator is a "clot-busting" drug that is often administered to people who have suffered a heart attack or stroke. A pig has been produced that can produce human hemoglobin. Artificial blood may soon be a reality. Cloning Mammals Cloning animals refers to producing offspring that are genetically identical to the animal being
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Unformatted text preview: cloned. This process has been done by removing the nucleus of an egg and replacing it with a diploid nucleus from the organism to be cloned. The egg is then treated so that it begins dividing. It is placed in the uterus of a host animal where it continues to grow. The Human Genome Project The Human Genome Project is a massive, government-funded project whose goal is to determine the base sequence of all of the human chromosomes. It would take 200 volumes of 1,000 pages each just to list the letters of the bases. Knowledge of the sequences of all genes making it easier to study, diagnose, and treat many kinds of human genetic diseases. Information on gene sequences is important in the development of gene therapy techniques. The information is expected to lead to a better understanding of genetic systems, and ultimately answers to mysteries surrounding such topics as gene regulation and cancer....
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