Chapter 19 October 12 - Cyanohydrins: 4 Nucleophilic...

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1 Acid­Catalyzed Hydration Reaction Mechanism: Catalyzation of Hydration Reactions Addition of H­Y to a carbonyl compound (ketones/aldehyde):
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2 Nucleophilic Addition of HCN: Cyanohydrin Formation General Reaction: Using HCN as the lone reactant Overall reaction rate can be increased if a small amount of base is present Reaction Mechanism:
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3 Useful Functional Group Transformations of
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Unformatted text preview: Cyanohydrins: 4 Nucleophilic Addition of Grignard and Hydride Reagents to Aldehydes and Ketones: Alcohol Formation Grignard Reaction Mechanism: Hydride Reaction Mechanism: 5 Nucleophilic Addition of Amines: Imine and Enamine Formation Addition of primary amines (RNH 2 ) and secondary amines (R 2 NH) to the aldehyde/ketone carbonyl group:...
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Chapter 19 October 12 - Cyanohydrins: 4 Nucleophilic...

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