Gallbladder Cancer - TAddona

Gallbladder Cancer - TAddona - Gallbladder Cancer...

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Unformatted text preview: Gallbladder Cancer Epidemiology • Incidence ~ 5000 • 5 th most common GI malignancy • Women > men • High incidence in S America (Chile) • ~ 1% of pt’s undergoing cholecystectomy for symptomatic gallstones Risk Factors • Gallstones • Gallbladder Polyps • Chronic Salmonella infection • Abnormal Pancreaticobiliary duct junction * Porcelain gallbladder * Age Presentation/Diagnostic Imaging • Presentation is non-specific • Diagnositic Imaging – Sono – CT – MR/MRCP – EUS Histology / Pathology * Progression to Ca may take up to 15 yrs • Adenocarcinoma 80-90% • Anaplastic 7% • Squamus 6% • Lymphoma, Sarcoma Staging Surgical Management • Only 10-30% resectable @ time of diagnosis • Three Presentations: – GB CA discovered during or after lap/open chole for assumed benign dz – GB CA suspected after diagnostic evaluation – GB CA advanced stage at presentation Surgical Options • Simple cholecystectomy • Radical cholecystectomy • Radical chole w/ anatomic liver resection • Radical chole w/ Whipple What to do during elective lap chole...
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Gallbladder Cancer - TAddona - Gallbladder Cancer...

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