Lec10CohortStudies(Revised07)

Lec10CohortStudies(Revised07) - Cohort Studies All studies...

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Unformatted text preview: Cohort Studies All studies involve some descriptive or analytic type of comparison of exposure and disease status. Analytical study design options include: observational or interventional (which one is based on the role of the investigator) . There are three basic types of observational analytical study designs: Cohort studies Case-control studies Cross-sectional studies Introduction Specific epidemiological study designs can be used to reveal etiologic (causal) relationships First, using observational analytical studies : Determine whether there is an association between a factor or a characteristic and the development of disease Second: From these associations, derive appropriate inferences regarding a possible causal relationship Introduction Analytical Studies Control and experimental groups Randomized groups data collected without bias Dependent and independent factors Group by common characteristics Start with a group of subjects who lack a positive history of the outcome of interest yet are at risk for it (cohort). Think of going from cause to effect. The exposure of interest is determined for each member of the cohort and the group is followed to document incidence in the exposed and non-exposed members. Cohort Studies When is a cohort study warranted? When good evidence suggests an association of a disease with a certain exposure or exposures. Changes and variation in the disease or health status of a study population as the study group moves through time. Generation effect Cohort Effect Prospective (concurrent) Retrospective (historical) Restricted (restricted exposures) Types of Cohort Studies Types of Cohort Studies Prospective cohort characterized by determination of exposure levels (...
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This note was uploaded on 12/21/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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Lec10CohortStudies(Revised07) - Cohort Studies All studies...

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