RPR test for syphilis

RPR test for syphilis - Rapid Plasma Reagin(RPR Syphilis is...

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Rapid Plasma Reagin (RPR)
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Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum . The RPR (Rapid Plasma Reagin) Card test is a presumptive serologic screening test for syphilis. The serum of a person with syphilis contains a non-specific anti-lipid antibody (termed reagin ), which is not found in normal serum.
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Syphilis infection starts the breakdown of the patient's own tissue cells. Fatty substances which are released, combine with protein from Treponema pallidum to form an antigen which stimulates the body to produce antibodies against both the body's tissue lipids (non-specific or non- treponemal) as well as the T. pallidum protein (specific or treponemal) . The RPR Card test detects the nonspecific antilipid antibody and is referred to as a non-treponemal test for syphilis .
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The RPR test is a non-treponemal slide agglutination test for the qualitative and semi-quantitative detection of plasma reagins in human serum. Carbon particles coated with a lipid complex
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This note was uploaded on 12/21/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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RPR test for syphilis - Rapid Plasma Reagin(RPR Syphilis is...

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