~BN10 postsynaptic potential

~BN10 postsynaptic potential - V m Inhibitory Postsynaptic...

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Postsynaptic Potentials Lesson 10
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Postsynaptic Potentials V m changes Excitatory: + Inhibitory: - ~
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Postsynaptic Potentials - PSPs Chemically-gated ion channels Graded Summation Duration 10 – 100 milliseconds Velocity Fast approximately speed of light Decremental Weaken over time & space ~
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Excitatory Postsynaptic Potential Depolarization (+) V m becomes more positive Na+ influx ~ EPSPs
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-55 mV - 65 mv AT REST V m Time EPSP + - Depolarization more likely to AP ~ Record here +
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AT REST Time Temporal Summation + - 2 pulses same synapse ~ + - 65 mv -55 mV V m
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AT REST Time + - Temporal Summation Repeated stimulation + - 65 mv -55 mV V m
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AT REST Time + - Spatial Summation + Multiple synapses + - 65 mv -55 mV
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Unformatted text preview: V m Inhibitory Postsynaptic Potential similar to EPSPs EXCEPT opposite hyperpolarization (-) V m becomes more negative K+ efflux ~ IPSPs AT REST Time IPSP +- Hyperpolarization less likely to fire also summate (max)-- 65 mv -55 mV V m EPSPs & IPSPs summate CANCEL EACH OTHER Net stimulation EPSPs + IPSPs = net effects *Integration ~-EPSP IPSP +- 65 mv Postsynaptic Potentials EPSP Excitatory Depolarization Na+ influx AP more likely IPSP Inhibitory Hyperpolarization K+ efflux AP less likely Soma & Dendrites Chemically-gated channels Passive current Graded Summation...
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~BN10 postsynaptic potential - V m Inhibitory Postsynaptic...

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