~BN12 synaptic transmission

~BN12 synaptic transmission - Synaptic Transmission Lesson...

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Synaptic Transmission Lesson 12
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Synapses Communication b/n neurons Electrical Electrotonic conduction Chemical Ligand / receptor ~
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Electrical Synapses Tight junctions Connexons Passive current Synchronous activity Breathing Hormone release from hypothalamus ~
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Synaptic Events Action Potential reaches axon terminal Chemical substance released Neurotransmitter (NT) Diffuses across synapse Binds to receptor protein EPSP or IPSP ~
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1. Precursor transport 2. NT synthesis 3. Storage 4. Release 5. Activation 6. Termination ~ Synaptic Transmission Model
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Presynaptic Axon Terminal Postsynaptic Membrane Terminal Button Dendritic Spine
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1. Precursor Transport
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E 2. Synthesis Enzymes & cofactors ~
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3. Storage E
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Synapse Terminal Button Dendritic Spine 3. Storage In vesicles
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Synapse Ca++ AP 4. Release via exocytosis diffusion
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Exocytosis: Membrane Fusion Ca 2+ influx 2 d messenger Ca 2+ -Calmodulin SNAPs soluble-NSF- attachment proteins SNAREs SNAP receptors ~
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5. Activation NT binds to receptor
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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~BN12 synaptic transmission - Synaptic Transmission Lesson...

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