~BN14 signal transduction

~BN14 signal transduction - Signal Transduction Lesson 14...

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Signal Transduction Lesson 14
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Ligands & Receptors Ligand Receptor proteins ligand binds to multiple receptors Binding site specific point of ligand & receptor Affinity attraction physical & electrical fit~
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Receptor Activation Structure-activity relationship Affinity Activation excitation or inhibition Drugs Change structure change affinity Agonists activate Antagonists no activation ~
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Chemical Signaling Mechanisms Synaptic Paracrine Medium range intercellular signaling Endocrine Hormones via blood Pheromones Via air ~
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Signaling Pathways Cell impermeant Requires receptors in membranes Cell permeant Lipid soluble Steroid hormones Cell-associated signaling molecules e.g., CAMs ~
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Receptor Types Channel-linked receptors Ionotropic Enzyme-linked receptors Protein kinases mostly
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~BN14 signal transduction - Signal Transduction Lesson 14...

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