~MS Treatment - Keely Perry

~MS Treatment - Keely Perry - Multiple Sclerosis &...

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Multiple Sclerosis & Treatment of Progression with Interferon- Beta-1a
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What is Multiple Sclerosis? Most commonly defined as an autoimmune disease that affects the CNS Characterized by the loss and/or damage of the myelin sheath Loss of myelin sheath results in the inability of neurons to transmit neural signals properly, causing the many symptoms of MS Unpredictable and no known cures
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Anatomy of the Neuron
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Four Major Varieties of MS Relapsing/remitting (RRMS) Characterized by periods of flare-ups and remission Accounts for 85% of MS patients Primary Progressive (PPMS) Slow continuous worsening of disease from onset Only about 10%
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Four Major Varieties of MS (cont.) Secondary Progressive (SPMS) Initial period of relapsing-remitting, then steady worsening of disease 50% of patients diagnosed with RRMS develop into this variety within 10 yrs without drug treatment Progressive Relapsing (PRMS) Steady worsening with acute relapses Different from RRMS in that disease progresses during relapses
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What Causes MS? Not exactly known Several theories Most common—myelin damage results from abnormal response in the immune system T cells (type of white blood cell) attack myelin Though to be triggered by environmental and/or genetic factors
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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~MS Treatment - Keely Perry - Multiple Sclerosis &...

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