12 - Bone Tumor - D3

12 - Bone Tumor - D3 - Bone tumors are rare tumors...

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Unformatted text preview: Bone tumors are rare tumors accounting for less than .2% of all cancers Occur more in young ages Classification of Bone tumors Origin: - primary- secondary: 95%, breast, lung, prostate, kidney and thyroid cell type: Bone Osteoma, osteosarcoma Cartilage Chondroma, Chondrosarcoma Marrow Hemangioma, angiosarcoma Fibrous tissue Fibroma, fibrosarcoma Tumor type: Benign: Osteoma, osteochondroma Malignant :: Osteosarcoma, chondrosarcoma Symptoms and Signs It may be asymptomatic and discovered accidentally. Pain : may worsen at night and awakes patient, caused by tumor compression on surrounding tissue, hemorrhage in the tumor, pathological fractures also cause pain Swelling . Local tenderness. Warmth Pathological fracture: may be the first sign. General: fatigue, fever, wt. loss A mass can be felt at the tumor site. Malignant vs. Benign Tumors Malignant vs. Benign Tumors Rapid growth, warmth, tenderness, and ill defined edges are suggestive of malignancy. INVESTIGATIONS History and examination Imaging Biopsy Labs Calcium: Greater than normal levels may indicate metastasis. Serum phosphorus: Greater than normal levels may indicate bone metastasis. PTH: Lower than normal levels may indicate bone metastasis. ALP isoenzyme: Higher than normal ALP levels may indicate Paget's disease, osteoblastic bone cancers, osteomalacia and rickets. LDH: High values indicate poor prognosis Plain x-ray Most useful Could see: A lump Bone destruction Cortical thickening + periosteal reaction Cysts Important to notice: Where How many Cystic or not Margins destruction Periosteal reaction...
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12 - Bone Tumor - D3 - Bone tumors are rare tumors...

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